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手术前后静脉注射地塞米松对预防PCA患者术后恶心呕吐作用的比较

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摘要 【目的】手术前后应用地塞米松预防病人自控镇痛(PcA)患者术后恶心呕吐的效果。【方法】随机将80例接受乳腺癌改良根治手术的女性患者分为两组,每组40例:术前组(n=40),麻醉诱导前静脉注射地塞米松10rag(2mL),术毕静脉注射生理盐水2mL;术毕组(n=40),麻醉诱导前静脉注射生理盐水2mL,术毕静脉注射地塞米松10mg(2mL)。术毕均行PCA。观察术后24h内病人镇痛效果、镇静评分和恶心呕吐发生情况。【结果】两组间镇痛效果、镇静评分无明显差异(P〉0.05)。术毕组恶心发生率为35%,呕吐发生率为25%,均分别明显高于术前组的15%和7.5%,且差异均有显著性(P〈0.05)。【结论】术前地塞米松注射预防乳腺癌改良根治术后静脉芬太尼镇痛相关的恶心呕吐的效果优于术毕。
出处 《医学临床研究》 CAS 2009年第8期1510-1511,共2页 Journal of Clinical Research
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