摘要
目的:探讨氧氟沙星诱发癫痫的相关危险因素,为临床安全用药提供依据。方法:收集中国知网和我院上报的氧氟沙星诱发癫痫的报道并汇总分析。结果:收集到氧氟沙星诱发癫痫25例,癫痫发作最短出现于用药后10min,最长于用药后第6天,发作持续时间最短1min,最长35min,最多发作3次,均好转出院。结论:口服和静滴氧氟沙星均可致癫痫,临床上应高度重视,合理使用,以保障患者用药安全。
Objective：To analyze and discuss the factors of seizure induced by Ofloxacin,to provide basis for safe application of Ofloxacin in clinical practice. Methods： The reports of seizure induced by Ofloxacin from CNKI and our hospital were reviewed and analyzed with excel. Results： 25 cases of seizure induced by Ofloxacin were collected,seizure occurred as early as 10 minutes after the medication, and occurred latest in the sixth day of the medication, seizure with a duration ranging from 1 minute to 35 minutes and with a frequency of 3 seizures, all the cases recovered and were discharged from hospital. Conclusion： Seizure can be induced by Ofloxaein from mouth and intravenous infusion,whieh should be rationally used, more attention should be paid in clinic so as to ensure safe medication.
出处
《中国医药导报》
CAS
2009年第25期112-113,共2页
China Medical Herald
