美林混悬液与复方氨基比林注射液治疗小儿高热100例疗效观察

Observation on therapeutic effect of Motrin Suspension and Compound Aminopyrine Injection for treating child high fever in 100 cases

目的评价美林混悬液与复方氨基比林注射液对小儿高热的退热疗效和安全性。方法将体温超过39.0℃的高热患儿100例,随机分为2组,分别给予美林混悬液口服和复方氨基比林肌肉注射治疗。结果美林组的退热开始时间、不良反应与复方氨基比林组相同,而退热效果、退热持续时间均优于复方氨基比林组。结论在小儿高热的临床治疗中,美林混悬液的退热作用强、维持时间长、不良反应少、安全可靠,避免了肌注带来的疼痛和不良反应,可替代复方氨基比林,值得临床推广应用。

Objective To evaluate the healing effect and safety of Motrin Suspension and Compound Aminopyrh ine Injection on children with high fever. Methods 100 children withigh fever whose body temperature higher than 39.0 ℃ ,were randomly divided into 2 groups, one group took Motrin Suspension and the other was injected with Compound Aminopyrine Injection. Results The start time of fever abatement and adverse events of both groups were the same,while the effect of fever abatement and duration of Motrin Suspension were superior to Compound Aminopyrine Injection. Conclusion In the clinical treatment of children with high fever,Motrin Suspension has stronger fever abatement effect,longer maintaining duration, less side effects and more safety and reliability. Besides, it avoids the pain from injection and side effects. So it can replace Compound Aminopyrine Injection and is worthy of clinical application.