动态血压监测评价替米沙坦治疗高血压的临床疗效

Evaluation on clinical efficacy of telmisartan in treating hypertension with ambulatory blood pressure monitoring

目的用24h动态血压监测评价替米沙坦治疗原发性高血压的临床疗效。方法选择70例原发性高血压患者,予以口服替米沙坦片80mg,每天1次,疗程4周,分别于用药前及用药4周后行24h动态血压监测。结果70例患者中显效19例,有效45例,总有效率91.43%;服药4周后与用药前相比24h昼夜平均血压、白天平均血压、夜间平均血压、白天最高血压、夜间最高血压及血压负荷值均明显降低,差异有统计学意义(P<0.01)。结论替米沙坦治疗原发性高血压疗效显著。

Objective To evaluate the clinical efficacy of telmisartan in treating primary hypertension with ambulatory blood pressure monitoring. Methods The patients with primary hypertension were given telmisartan 80mg four times daily for four weeks. Ambulatory blood pressere monitoring was done before and after treatment respectively. Results In 70 patients, 19 patients got significant efficiency,45 patients got efficiency, total effective rate was 91.43 %. Campared before treatment with after 4-week treatment,mean blood pressure in all day and all night,mean blood pressure in daytime, mean blood pressure in night time, the peak blood pressure in daytime, the peak blood pressure in nighttime and burden of blood pressure all decreased significantly （P〈0.01）. Conclusion Treaing primary hyoertension with telmisartan can get significant efficacv.