血清β-人绒毛膜促性腺激素及孕酮监测在氨甲喋呤治疗异位妊娠中的临床价值

Clinical value of serum β-HCG and progesterone monitoring in therapy of ectopic pregnancy with MTX

目的探讨血清β-人绒毛膜促性腺激素(β-HCG)及孕酮动态监测在氨甲喋呤(MTX)治疗异位妊娠中的临床价值。方法回顾性分析MTX治疗异位妊娠32例。结果治疗成功组β-HCG及孕酮与治疗失败组相比具有显著差异性,治疗后孕酮比β-HCG更早降至正常范围内。结论治疗前β-HCG及孕酮是影响治疗效果的重要因素,治疗后的β-HCG及孕酮动态监测对判断治疗效果有着重要作用。

Objective To probe the clinical value of serum β-HCG and progesterone monitoring in the therapy of ectopic pregnancy with MTX.Methods 32 cases with ectopic pregnancy treated with MTX were analyzed.Results In successful group,the serum β-HCG and progesterone were significantly lower than those in the failed group before treatment,progesterone dropped more fastly to normal range than β-HCG after treatment.Conclusion The serum β-HCG and progesterone level before treatment are the important factors for effectiveness of MTX therapy. Monitoring the level of β-HCG and progesterone were important for estimating the effectiveness of MTX therapy.