细菌性阴道病和支原体感染的相关性分析

The relationship between bacterial vaginosis and the infection of mycoplasma in genitourinary tract

目的:评估细菌性阴道病(bacterial vaginosis,BV)与解脲脲原体(Ureaplasma urealyticum,UU),人型支原体(M.hominis,MH)感染的相关性。方法:根据Amsel标准分组,选BV组81例,非BV组(包括念珠菌性阴道炎,滴虫性阴道炎等)75例,健康体检者52人。取宫颈分泌物做支原体培养,判断支原体感染与BV的相关性。结果:BV组支原体培养阳性56例(69.1%),非BV组30例(40.0%),体检组16人(30.8%)。BV组的感染以MH或MH+UU混合感染为主,其余两组以单纯UU感染为主。结论:UU和MH相互协同作用是BV的致病机制之一。

Objective： To evaluate the relationship between bacterial vaginosis （BV） and the infection of mycoplasma in genitourinary tract. Methods： Based on Amsel criteria, 81 patients with BV, 75 patients with non-BV （ including mycotic vaginitis, trichomonas vaginitis, etc. ） were selected and 52 healthy women used as controls. The vaginal discharge was cultured for mycoplasma with liquid and solid medium. The relationship between BV and mycoplasma was analyzed. Results： The infection rates of mycoplasma in BV group, non - BV vaginitis group and control group were 69.1%, 40.0 % and 30.8 %, respectively, with significant differences between the three groups （P 〈 0.05）. M. hominis （MH） or mixed infection of MH and Ureaplasma urealyticum （UU） was common in BV group, while in other two groups UU infection was dominating. Condusion： The synergic effect of MH and UU may be one of the major pathogenes in BV.