正常成人伏隔核体积磁共振测量初探

Volume Measurement of Nucleus Accumbens in Healthy Adults by MR:an Initial Study

目的:利用3.0磁共振分析成人伏隔核体积双侧差异及性别差异。方法:健康志愿者42例(男24例,女18例),年龄范围18～55岁,中位年龄25岁,利用磁共振对伏隔核进行常规扫描和冠状面容积扫描。在容积扫描图像上对伏隔核分割并进行体积测量,比较双侧体积差异及性别差异。结果:所有志愿者以及男、女性志愿者伏隔核平均体积均右侧大于左侧(P<0.001)。男女之间伏隔核总体积差异不存在统计学意义(P>0.05)。结论:健康成人右侧伏隔核体积大于左侧,性别之间伏隔核总体积无明显差异。

Objective：To measure the volume of nucleus accumbens by means of 3.0T MR scanner and analyze the difference between both sides of the brain and between males and females. Methods：42 healthy volunteers （24 males and 18 females） ,ranging from 18 years to 55 years （median age 25 years）, underwent the routine scan and volume scan by MR imging examination of the brain. The volumes of nucleus accumbens on both sides were measured and the differences be tween two sides and different genders were analyzed. Results：Among males, females or total volunteers the average volume of nucleus aceumbens on the right side is significantly larger than that on the left side （P^0. 001）. No significant difference of the total volume between males and females was found （P^0.05）. Conclusion： Among healthy adults, the volume of nu- cleus accumbens on the right side is larger than that on the left. There is no significant difference of total volume of nucleus accumbens between males and females.