微量白蛋白尿水平对急性ST段抬高性心肌梗死患者预后的影响

Effects of Admission Microalbuminuria on Prognosis in ST-segment Elevation Myocardial Infarction Patients

目的:探讨入院微量白蛋白尿水平升高的急性ST段抬高性心肌梗死(STEMI)患者基线水平特征及对预后的影响。方法:入选STEMI患者93例。均给予最优的介入和药物治疗;根据入院次日微量白蛋白尿水平分为尿微量白蛋白升高组(A组)48例和尿微量白蛋白正常组(B组)45例,观察并比较两组患者基线水平特征,及院内的病死率和主要不良心脏事件(MACE,包括死亡、心肌梗死、需要血运重建的心绞痛)的发生率。结果:单因素变量分析显示,基线水平两组患者在肌酐清除率、血糖、血沉指标上具有统计学差异,A组患者住院期间病死率和主要不良心脏事件发生率较B组组升高,且有统计学意义。结论:STEMI患者入院时尿微量白蛋白水平可预测患者预后。

Objective： To evaluate the effects of admission microalbuminuria on prognosis in acute ST-segment elevation myocardial infarction （STEMI） patients. Method： A total of 93 patients of STEMI were studied. Patients were divided into 2 groups according to admission microalbuminuria level： elevated group and normal microalbuminuria group. Mortality and majour adverse cardiac events （MACE, including death, myocardial infarction, recurrent angina needing revascularization） were followed up in hospital in the two groups. Results ： Univariate analyses showed statistical differences between normal and elevated microalbuminuria groups in creatinine clearance rate, erythrosedimentation, blood glucose on presentation. There were higher inhospital mortality, artd MACE in elevated group than normal group. Conclusions ： In STEM1 patients, mostly undergoing primary PCI, the level of microalbuminuria was an independent predictor for poor prognosis.