临床分离主要病原菌菌群分布及耐药分析

目的了解临床常见病原菌菌群分布及耐药情况,为临床经验用药提供参考依据。方法对临床分离病原菌进行统计和分析。结果共分离病原菌3586株,革兰阴性菌1953株,革兰阳性菌1433株。药敏结果显示,革兰阳性球菌对万古霉素、氨苄西林/舒巴坦、利福平高度敏感;革兰阴性杆菌对亚胺培南、阿米卡星、敏感性较高。结论肠杆菌科大肠埃希菌耐药率高于肺炎克雷伯菌,非发酵菌的鲍曼不动杆菌、铜绿假单胞菌显示多重耐药。

Objective To investigate the distribution and antimicrobia resistance of common pathogenic bacteria in our hospital to provide scientific data for the experienced clinical application of antibiotics. Methods Retrospective statistics and analysis was performed on bacterial strains isolated from our hospital in 2007. Results A total of 3586 pathogenic strains were isolated, among which 1953 strains were Gram-negative organisms and 1433 strains were Gram-positive ones. The results of bacterial susceptibility tests suggested that gram-positive cocci was hypersensitive to vancomycin, ampicillin-sulbactam, and rifampicin, and gram-negative bacilli was highly sensitive to imipenem and amikacin. Conclusion Among Enterobacteriaceae, the drug-resistance rate of Escherichia coli was higher than klebsiella pneumoniae; Acinetobacter baumanii and Pseudomonas aeruginosa, which belong to nonfermentative gram-negative bacilli, showed multiple drug resistance.