1McClain MT, Heinlen LD, Dennis GJ, et al. Early events in lupus humoral autoimmunity suggest initiation through molecular mimicry[J] Nat Med, 2005, 11 (1):85-89.
3Wang S, Rowe M, Lundgren E. Expression of the EpsteinBarr virus transforming protein LMPI causes a rapid and transient stimulation of the Bcl-2 homologue Mcl-1 levels in B-cell lines[J]. Cancer Res, 1996, 56(20): 4610-4613.
4Lenert P, Goeken A , Handwerger BS , et al. Innate immune responses in lupus-prone Palmerston North mice : differential responses to LPS and bacterial DNA/ CpG oligonucleotides [J]. J ClinImmunol, 2003, 23(3) :202-213.
5Pawar RD, Patole PS, Ellwart A, et al. Ligands to nucleic acid specific toll-like receptors and the onset of lupus nephritis[J]. J Am Soc Nephrol, 2006, 17(12): 3365-3373.
6Iehikawa HT, Williams LP, Segal BM. Activation of APCs through CD40 or Toll-like receptor 9 overcomes tolerance and precipitates autoimmune disease[J]. J Immunol, 2002, 169 (5): 2781-2787.
7Sekigawa I, Kawasaki M, Ogasawara H, et al. DNA methylation: its contribution to systemic lupus erythematosus[J]. Clin Exp Med, 2006, 6(3) : 99 -106.
8Holers VM. Complement deficiency states, disease susceptibility, and infection risk in systemic lupus erythematosus[J]. Arthritis Rheum,1999, 42(10) : 2023- 2025.
9Takahashi R, Tsutsumi A, Ohtani K, et al. Association of mannose binding lectin (MBL) gene polymorphism and serum MBL concentration with characteristics and progression of systemic lupus erythematosus[J], Ann Rheum Dis,2005, 64 (2): 311-314.
10Kang I, Park SH. Infectious complications in SLE after immunosuppressive therapies[J]. Curr Opin Rheumatol, 2003, 15(5): 528-534.
8Bosch X, Guilabert A, Pallares L, et al. Infections in systemic lupus erythematosus:a prospective and controlled study of 110 patients [J]. Lupus,2006,15 (9) :584 -599.
9Al-Rayes H,Al-Swailem R, Arfin M, et al. Systemic lupus erythe- matosus and infections:a retrospective study in Saudis [J]. Lupus, 2007,16(9) :755 -763.
10Ng WL, Chu CM, Wu AK, et al. Lyrnphopenia at presentation is associated with increased risk of infections in patients with systemic lupus erythematosus [ J ]. QJM ,2006 ,99 ( 1 ) : 37 - 47.
