尿道内置导管对前列腺增生患者尿流率测定的影响研究

Impact of 8F intra-urethral catheter on uroflow rate in pressure-flow studies in patients with benign prostatic hyperplasia

目的探讨良性前列腺增生患者尿道内置8F测压管在压力-流率测定中对尿流率的影响。方法对103例良性前列腺增生（BPH）患者术前进行自由尿流率和尿动力检查，其中逼尿肌功能收缩良好组89例，逼尿肌功能收缩无力组14例。压力-流率测定中尿道内放置8F测压导管，分析比较自由尿流率和置管后尿流率的变化。结果103例患者自由尿流率和带管尿流率的排尿量分别为（177．68±70．55）ml和（180．90±68．34）m1（／54）．05）。逼尿肌功能收缩良好组89例自由尿流率和带管尿流率的Qmax，（10．2±3．1）ml／s、Qmax（7．8±3．9）ml／s（P〈0．05），逼尿肌功能收缩无力组14例自由尿流率和带管尿流率的Qmax（9．1±4．1）ml/s、Qmax（5．8±3．2）ml/s（P〈0．05）。两组的Qmax，下降值分别为（2．9±2．8）ml／s和（3．4±2．9）ml／s，组间比较差别有显著性意义（P〈0．05）。结论良性前列腺增生患者尿道内置8F测压导管可影响最大尿流率测定值，有逼尿肌功能受损时可能影响更大，临床上在进行压力-流率结果分析时应充分加以考虑以便能更加客观、正确地加以评价。

Objective To investigate the impact of 8F intra-urethral catheter on uroflow rate in pressure- flow studies in patients with benign prostatic hyperplasia. Methods one hundred and three men with lower urinary tract symptoms underwent free uroflometry and pressure-flow study respectively. With an 8F urethral catheter, we recorded the standard pressure-flow variables such as uroflometry, detrusor pressure at maximum uroflow and so on. We analyze free uroflow rate and catheter＇s uroflow rate with paired t-test.Results The maximum voided volume in free uroflometry and in pressure-flow study were （177.68 ± 70.55）ml and （180.90 ± 68.34）ml respectively. The maximum free uroflow rate and the maximum catheter＇s uroflow rate were （10.2 ± 3.1）ml/s and （7.8 ± 3.9 ）ml/s in BPH with detrusor normal-activity group （ P〈0.05 ）, （9.1 ±4.1）ml/s and （5.8 ± 3.2）ml/s in BPH with detrusor under- activity group（ P〈0.05 ）. The differences of uroflometry between two voids in tow groups were （2.9 ± 2.8）ml/ s and （3.4 ± 2.9）ml/s（ P〈0.05 ）. Paired t-test showed that there was significant difference between the maximum free uroflow rate and maximum catheter＇s uroflow rate.Conclusions 8F urethral catheter appeared to have a significant impact on maximum uroflow rate in benign prostatic hyperplasia and there was more significant impact in BPH with detrusor under- activity group. It must be considered when analyzing pressure flow parameters to make a accurate diagnosis.