血清肺炎支原体抗体效价测定的临床应用

The clinical application of Mycoplasma pneumonia serum antibody titers test

目的采用SERODIA—MYCOII肺炎支原体诊断试剂盒检测患者血清中肺炎支原体（Mp）抗体效价，探讨其在临床上的应用价值。方法采集患者静脉血，血清作倍比稀释，用日本富士肺炎支原体诊断试剂盒SERODIA—MYCOII作颗粒凝集试验，并对测定结果进行分析。结果1164例被检血清中，血清抗体阳性者505例（效价〉1：40），阳性率为43．27％。〈5岁组阳性率为23．85％，且抗体效价较低，以1：40和1：80多见；5—14岁阳性率为60．57％；〉14岁阳性率为35．74％，且抗体效价较高，多在1：160以上。结论SERODIA—MYCOII检测血清中Mp抗体效价具有敏感性高、特异性强、重复性好等特点，值得临床推广作为实验室筛查Mp感染的常规方法。

Objective In order to investigate the application of its clinical study, mycoplasma pneumonia （Mp） antibody titers in patients were detected with SERODIA-MYCOII kit. Methods Patients＇ blood serum were collected and diluted for the times with Mycoplasma pneumoniae SERODIA-MYCOII kit produced by Japan＇s Fujirebio for particle agglutination test, and results were analyzed, Results The results of 1, 164 cases, 505 cases were positive （titer〉 1： do）, the positive rate was 43.27 %. Below 5 years old group, the positive rate was 23.85 %, and the antibody titers of 1： 40 and 1：80 were predominant and its titers were lower. In 5 to 14-year-old group, the positive rate was 60.57%. In above 14-year-old group, the positive rate was 35.74 %, and the antibody titers were more than 1： 160. Conclusions SERODIA-MYCOII Mp in serum antibody titers with high sensitivity and specificity, repeatable, and other characteristics, it is worth promoting as a clinical laboratory screening Mp infection of conventional methods.