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STAT3在肿瘤中的作用研究进展 被引量：3

Research Progress in Role of STAT3 in Tumor
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摘要 STAT3的异常表达和活化与肿瘤的发生、发展及恶性生物学行为关系密切。全文对STAT3在细胞中的作用和临床应用作一综述。
作者 武巧丽 姜达
机构地区 河北医科大学第四医院
出处 《肿瘤学杂志》 CAS 2009年第8期766-768,共3页 Journal of Chinese Oncology
关键词 STAT3 肿瘤 转录 靶点
分类号 R730.23 [医药卫生—肿瘤]
  • 相关文献

参考文献21

  • 1Yu H, Jove R. The STATs of cancer-new molecular targets come of age[J]. Nat Rev Cancer, 2004, 4(2):97-105.
  • 2Darnell JE Jr.Transcription factors as targets for cancer therapy[J]. Nat Rev Cancer, 2002, 2(10):740-749.
  • 3Schindler CW. Series introduction. JAK-STAT signaling in human disease[J]. J Clin Invest, 2002, 109(9):1133-1137.
  • 4Zhang Y, Turkson J, Carter-Su C, et al. Activation of STAT3 in v-Src-transformed fibroblasts requires cooperation of Jakl kinase activity [J]. J Biol Chem, 2000, 275 (32):24935-24944.
  • 5Kisseleva T, Bhattacharya S, Braunstein J, et al. Signaling through the JAK/STAT pathway, recent advances and future challenges[J]. Gene, 2002, 285(1-2): 1-24.
  • 6Niu G, Wright KL, Huang M, et al. Constitutive STAT3 activity up-regulates VEGF expression and tumor angiogenesis[J]. Oncogene, 2002, 21(13) :2000-2008.
  • 7Bromberg JF, Wrzeszczvnska MH, Devgan G, et al. STAT3 as an oncongene[J]. Cell, 1999, 98(3):295-303.
  • 8Bowman T, Garcia R, Turkson J, et al. STATs in oncogenesis[J]. Oncogene, 2000, 19 (21):2474-2488.
  • 9Alvarez JV, Febbo PG, Ramaswamy S, et al. Identification of a genetic signature of activated signal transducer and activator of transcription 3 in human tumors [J]. Cancer Res, 2005, 65(12):5054-5062.
  • 10Dauer D J, Ferraro B, Song L, et al. STAT3 regulates genes common to both wound healing and cancer [J]. Oncogene, 2005, 24(21):3397-3408.

同被引文献24

  • 1Deng-Fu Yao, Xin-Hua Wu, Yong Zhu, Gong-Sheng Shi, Zhi-Zhen Dong, Deng-Bing Yao, Wei Wu, Li-Wei Qiu and Xian-Yong Meng Nantong, China Research Center of Clinical Molecular Biology , Department of Pathology and Department of Gastroenterology , Affiliated Hos- pital of Nantong University,Department of Diagnostics , and Institute of Neurosciences , Nantong University,Nantong 226001, China.Quantitative analysis of vascular endothelial growth factor, microvascular density and their clinicopathologic features in human hepatocellular carcinoma[J].Hepatobiliary & Pancreatic Diseases International,2005,4(2):220-226. 被引量：81
  • 2温韬,钱海利,谢立,贺立香,黄德庄.肝癌患者血管内皮生长因子、内皮素和一氧化氮的水平变化及其意义[J].中华肝脏病杂志,2004,12(7):441-441. 被引量：7
  • 3谢一利,楼丽广.表皮生长因子受体信号通路及其靶向肿瘤治疗[J].国外医学（肿瘤学分册）,2005,32(5):361-364. 被引量：8
  • 4Kim ES,Hirsh V,Mok T,et al.Gefitinib versus docetaxel in previously treated non-small-cell lung cancer INTEREST:randomised phase Ⅲ trial[J].Lancet,2008,372 (9652):1809-1818.
  • 5Raben D,Bianco C,Milas L,et al.Targeted therapies and radiation treatment of head and neck cancer:are we making progress[J].Semin in Radiat Oncol,2004,14(2):139-152.
  • 6Chua DT,Nicholls JM,Sham JS,et al.Prognostic value of epidermal growth factor receptor expression in patients with advanced stage nasopharyngeal carcinoma treated with induction chemotherapy and radiotherapy[J].Int J Radiat Oncol Biol Phys,2004,59(1):11-20.
  • 7陈永杰,付艳忠,赵志华.原发性肝癌组织中血管内皮生长因子、微血管密度检测[J].郑州大学学报（医学版）,2007,42(5):925-927. 被引量：9
  • 8Bareschino MA, Schettino C, Rossi A,et al.Treatment ad- vanced non small cell lung cancer[J ].J Thoeac Dis,2011,3 (2): 122-133.
  • 9Gridelli C, Maione P, Rossi A, et al.Pemetrexed in advanced non small cell lung cancer[J ].Expert Opin Drug Saf, 2011, 10(2) :311-317.
  • 10Spitzner M,Roesler B,Bielfeld C,et al.STAT3 inhibition sensitizes colorectal cancer to chemoradiotherapy in vitro and in vivo[J].International Journal of Cancer,2014,134 (4) :997-1007.

引证文献3

二级引证文献11

肿瘤学杂志
2009年 第8期

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