摘要
为了达到高质量降压效果,医学界正致力于寻找新的作用靶点,研发新型降压药。本文阐述了新型降压药物选择性醛固酮受体拮抗剂、D1受体激动剂、中性内肽酶-血管紧张素转化酶双重抑制剂、肾素抑制剂、内皮素受体阻断剂、钾通道开放剂、一氧化氮、T型钙通道阻滞剂的作用机制、药物特性和代表药物。高血压是一种多基因遗传性疾病,基因治疗是目前高血压治疗研究的热点。本文也介绍了高血压的基因治疗研究进展。
In order to achieve high quality antihypertensire effect. It＇s necessary to develop new antihypertensive drugs. This paper expounds new antihypertensive medications, including the mechanism of action, the drug characteristics and representatives of new antihypertensive medications, such as selective aldosterone receptor antagonist, D1 receptor agonist, endo- peptidase-angiotensin converting enzyme inhibitor,renin inhibitor, endothelin receptor blockers, potassium channel opener, nitrogen monoxidum ,T-calcium channel blockers. Hypertension is a polygenic inheritance disease and gene therapy is a hot spot of currently hypertension treatment research. This paper introduces the research progress of gene therapy of hypertension.
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2009年第9期789-791,共3页
Chinese Journal of Practical Internal Medicine
关键词
高血压
降压药物
基因治疗
hypertension
antihypertensive drug
gene therapy
