Clinical Study on Combined Needle-embedding and Medication for Depressive Sleep Disorder

Objective： To observe the clinical efficacy of combined needle-embedding and SSRIs for depressive sleep disorder. Method： Upon admission, 71 depression cases were randomized into needle-embedding group of 24 cases, using combined needle-embedding and SSRls, acupuncture group of 21 cases, using combined acupuncture and SSRIs, and medication group of 26 cases, using SSRIs alone. Alter 1, 2, 4 and 6 weeks of treatment, the HAMD sleep scores were compared. Result： The HAMD sleep scores in the needle-embedding and acupuncture group were remarkably superior to the medication group and there was significant statistical difference after 1, 2 and 4 weeks of treatment （P〈0.01）. However, there was no statistical difference after 6 weeks of treatment. Conclusion： SSRIs can improve HAMD sleep scores. The combined needle-embedding or acupuncture with SSRIs can work faster and better than medication alone. There was no statistical difference between needle-embedding and acupuncture group, however, needle-embedding can reduce the treatment frequencies and therefore has more active clinical meaning.

目的:观察埋针结合SSRIs类药物治疗抑郁症睡眠障碍的临床疗效。方法:将71例抑郁症患者按入院先后顺序随机分为3组,埋针组24例,采用埋针结合SSRI类药物治疗;针刺组21例,采用针刺结合SSRi类药物治疗;药物组26例,采用单纯SSRI类药物治疗。观察3组治疗前及治疗1、2、4、6星期后HAMD睡眠积分的差异。结果:埋针组和针刺组HAMD睡眠积分的改善显著优于药物组,在治疗1、2、4星期后,与药物组差异均有统计学意义(P<0.01);治疗6星期后,3组间差异没有统计学意义。结论:SSRI类药物治疗可以改善HAMD睡眠积分。埋针和针刺配合SSRIs类药物改善抑郁症睡眠障碍效果好,且起效迅速,疗效优于单纯SSRIs类药物治疗。埋针组与针刺组差异无统计学意义,但由于埋针治疗减少了治疗的频次,故有积极的临床意义。