急性脑卒中早期营养状况及预后

Effect of Enteral Nutrition Support on Prognosis in Patients with Acute Stroke

目的:探讨早期肠内营养治疗能否改善急性卒中的近期预后。方法:采用前瞻性非随机对照研究,146例急性卒中伴吞咽障碍患者中;研究组(肠内营养)75例,对照组(家庭喂养饮食)71例。观察入院第1天、7天及90天后两组患者营养状态,同时比较入院7天和90天后(3个月)NIHSS评分。结果:住院7天,研究组营养指标显著优于对照组、营养不良发生率显著低于对照组;90天后研究组的NIHSS显著优于对照组;结论:早期肠内营养治疗能够改善急性卒中神经功能的近期预后。

Objective： To investigate the effect of enteral nutrition support on prognosis in patients with acute stroke. Methods： 146 cases of acute stroke were divided into nutrition--supported group（75 cases） and control group（71 cases） randomly. All patients were treated by conventional therapy. Nutrition--supported group received high--energy nutrition diet and control group received common liquid diet by nasal feeding. The levels of hemoglobin, serum albumin, prealbumin, triacylglycerol, neurologic impairment score（NIHSS）, the incidence rates of hypoproteinemia and infective complications were assessed at the 1st d, the 7th d and the 90st d after admission. Results： The nutrition indeces in both groups were descend at the 7th d and the 90st d after admission in both groups, and there were significantly lower in the control group than those in nutrition--supported group（allP〈0. 05） ;the incidence rates of hypoproteinemia and in the control group were obviously higher at the 7th d and the 90st d（P〈0. 05）. NIHSS in both groups were improved at the 90st d, while more significantly in nutrition--supported group （P〈0. 05）. Conclusion： Early enteral nutrition support can significantly improve nutritional status and helpful for clinical prognosis.