血尿酸水平与急性脑梗死相关性分析

Correlation between the level of serum uric acid and acute cerebral infarction

目的探讨血尿酸水平与急性脑梗死发病及预后的关系。方法选取住院急性脑梗死患者89例为观察组,检测入院24 h内血尿酸水平,并与正常对照组比较和分析两组间的相关性;分别对观察组病例入院第1天及第28天进行神经功能缺损评分,分析神经功能缺损与入院时血尿酸水平的相关性。结果急性脑梗死患者血尿酸水平及异常率明显增高,与对照组之间存在显著差异(P<0.01);在急性脑梗死患者中,血尿酸异常组较正常组入院第28天神经功能缺损的程度存在显著差异也较重,存在显著差异(P<0.01)。结论血尿酸水平与急性脑梗死的发病密切相关,参与了其发病机制,是预后不良的预测因素。

Objective To study the correlation between the level of serum uric acid and the prognosis of acute cerebral infarction. Methods A total of 89 patients with acute cerebral infarction were enrolled. The level of serum uric acid in 24 hours in hospitalwere examined and the correlation was analysed between normal group and patient group. The incompetent functions of the nerves of the patient group were rained on the lstday the 28th day in hospita, and tile relation of the incompetent functions of the nerves and the level of serum uric acid was analysed. Results The level of serum uric acid and the abnormal rate of the acute cerebral infarction patients increased obviously and there were significant diferent coinpared with the normal group （P 〈 0. 01 ） ; In the abnormal serum uric acid group of the acute cerebral infarction patients the degree of the incompetent func- tions of the nerves was much more serious on the 28th day in hospital（ P 〈 0. 01 ）. Conclusion The level of se- rum uric acid was a clos relation with acute cerebral infarction, and. was bad prognostic the predictable factor.