静脉丙种球蛋白治疗婴儿重症肺炎合并心力衰竭疗效观察

Intravenous immunoglobulin treatment of infants with severe pneumonia with heart failure Clinical Observation

目的观察婴儿重症肺炎合并心力衰竭患儿静脉滴注丙种球蛋白(IVIG)疗效、治愈率、住院天数。方法采用本院1994年1月至2004年12月住院病历14例在用抗生素、强心利尿剂等对症治疗时,同时加用IVIG静脉滴注300～500 mg/(kg.d),共3 d,并与18例重症肺炎合并心力衰竭患儿作对照。结果IVIG治疗婴儿重症肺炎合并心衰与对照组疗效比较有显著意义(X=4.23,P<0.05),治愈率比较无效(X=1.66,P>0.05),住院天数比较有显著意义(t=1.90,P<0.05)。结论重症肺炎合并心衰静脉滴注IVIG有较好临床疗效。

Objective Observation of the infant with severe pneumonia with heart failure in children with intravenous gamma globulin （IVIG）effect, the cure rate, the number of days hospitalized. Methods Used in January 1994-December 2004 medical records of 14 patients hospitalized with antibiotics, symptoms such as cardiac diuretic therapy,intravenous infusion of IVIG at the same time plus 300 -500 mg/（ kg · d） × 3 d, and 18 cases of severe pneumonia for the control patients with heart failure. Results IVIG treatment of infants with severe pneumonia with heart failure compared with the control group effect was significant （ X = 4. 23, P 〈 0.05 ） , compared the cure rate was invalid（ X = 1.66, P 〉 0.05 ） ,length of hospital stay was significantly more （ t = 1.90, P 〈 0. 05 ）. Conclusion Intravenous heart failure combined with severe pneumonia have a better clinical effect of IVIG.