非小细胞肺癌靶向治疗的前途与困惑

Molecularly Targeted Therapy for Non-Small-Cell Lung Cancer

靶向治疗是运用抗肿瘤药物靶向性与肿瘤的不同特异性位点结合发生作用从而抑制肿瘤细胞生长的一种治疗手段。针对恶性肿瘤中的非小细胞肺癌,其在临床中取得了一定成效。然而,其中仍存在很多问题。本文针对吉非替尼在非小细胞肺癌中的运用,及其优点和所面临的问题,阐述如何应对完善靶向治疗的挑战。

Molecularly targeted therapy could inhibit cancer cell differentially with less side effects, and it is increasingly common in cancer therapy, especially for the non--small--cell lung cancer. However, there remain many problems such as the limitation of its usage in high mutating cancer and its different effect on different races. In conclusion, clinical oncologists should see the bright future and the challenge of molecularly targeted treatment.