早期肠内营养在重症急性胰腺炎中的意义

Early enteral nutrition in severe acute pancreatitis

目的评价早期放置鼻空肠营养管行肠内营养（EN）对重症急性胰腺炎（SPA）的疗效。方法分析36例SPA患者的临床资料，按全肠外营养（TPN）和肠内营养（EN）随机分成两组，每组18例。比较两组患者治疗后的免疫、营养状况及平均住院天数、感染率及高血糖的发生率。结果两组的血清白蛋白、前白蛋白显著升高。EN组的感染率、平均住院天数、高血糖发生率均低于TPN组（P〈0．05）。结论早期EN在SPA治疗中起重要作用，合理应用有助于改善机体免疫及营养状况。

Objective To evaluate the therapeutic effects of early enteral nutrition（EN） in the treatment of severe acute pancreatitis. Methods Thirty-six case of SPA were analyzed and divided into EN group （ 18 patients） and total parenteral nutrition （TPN） group （ 18 patients）. The immunity, nutrition status, median duration of hospital stay, infection rate and the incidence of hyperglycemia between the two groups were compared. Results After nutrition therapy, the serum contents of albumin were increased obviously. The incidence of infection, median duration of hospital stay and the incidence of hyperglycemia in EN group were lower than those in TPN group （P 〈 0. 05 ）. Conclusion Early EN plays an important role in the treatment of SPA. Reasonable EN could improve the immunity and nutrition status of the SPA patients.