氯比格雷治疗不稳定心绞痛临床疗效分析

目的观察波立维(氯比格雷)不稳定心绞痛中在的疗效。方法2组均给予阿司匹林、低分子肝素、硝酸甘油、β受体阻滞剂等常规治疗,A组给予氯比格雷75mg,1次/d,随访1年;对照组B组给予安慰剂,观察心血管事件、猝死、脑卒中及上消化道出血发生率。结果波立维(氯比格雷)组心脑血管事件共发生3例(6.0%),而安慰剂组心脑血管事件共发生12例(24%),2组比较差异有显著性(P<0.05)。结论氯比格雷在不稳定心绞痛中有较好的疗效。

Objective Observation the curative effect of clopidogrel on the UAP.Methods Two groups general treat by asprin,low molecular heparin,glyceryl trinitrate,β-blocker,group A given by clopidogrel 75mg qd,allow search for one year;comparison group B given by console dose,observe the heart atherothrombotic event,abrupt die,cerebral accidente,alimentary tract bleeding.Results group of clopidogrel all happened 3 accidents（6.0%）,Group B have 12 accidents（24%）.Two groups have notability difference（P 〈0.05）.Conclusion Clopidogrel have better effect on the treatment in UAP.