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HCG注射日孕激素水平对卵巢储备能力正常者IVF妊娠结局的预测价值 被引量：7

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摘要 目的评估正常卵巢储备功能的不孕症患者体外受精-胚胎移植(in vitro fertilization-embryotransfer,IVF-ET)中HCG注射日血清孕激素(progesterone,P)水平以及P与雌二醇(estradiol,E2)比值对IVF-ET临床妊娠的预测价值。方法选择卵巢储备能力正常且采用长方案治疗的120例患者进行回顾性研究。在HCG日测定血清E2和P水平,胚胎移植后4周经阴道B超确定临床妊娠。采用受试者工作特征曲线(ROC曲线)评价HCG日P水平和P/E2值预测IVF-ET临床妊娠的敏感性及特异性。结果ROC曲线显示HCG注射日P水平及P/E2值用于预测临床妊娠无统计学意义(P=0.947,P=0.148),曲线下面积分别为0.505±0.068和0.598±0.067,面积的95%可信区间均包括0.5。结论对卵巢储备能力正常且采用长方案治疗的不孕症患者,HCG日P水平及P/E2值不能预测IVF妊娠结局。
作者 郭洪胜 李红 全松 邢福祺
机构地区 南方医科大学南方医院妇产科生殖医学中心 广东医学院组织胚胎学教研室
出处 《广东医学》 CAS CSCD 北大核心 2009年第9期1329-1331,共3页 Guangdong Medical Journal
关键词 体外授精-胚胎移植 HCG日 孕激素 P/E2 不孕症
分类号 R321-33 [医药卫生—人体解剖和组织胚胎学] R541.4 [医药卫生—心血管疾病]
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参考文献19

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广东医学
2009年 第9期

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