门静脉血栓形成的诊断与治疗

Diagnosis and Treatment of Acute Portal Vein Thrombosis

目的:探讨门静脉血栓形成的诊断与治疗方法。方法:15例门静脉血栓形成患者行抗凝、溶栓、祛聚治疗。结果:6例门静脉部分或完全再通,2例出现小肠坏死转为手术治疗,1例死亡,6例好转。手术患者无并发症和死亡。15例2周后血清D-dimmer水平明显下降(P<0.05)。结论:门静脉血栓形成应早期诊断,根据具体的病情选择合理的治疗方法。

Objective To explore the effective methods of diagnosis and treatment of portal vein thrombosis. Methods Retrospective analysis of the diagnosis and treatment of 20 patients with acute portal vein thrombosis was made. Results Fifteen patients were treated with anticoagulation, thrombolysis and antiplatelet therapy. The portal vein became partial/complete recanalization in 6 of them, 2 patients of them received operation because of bowel infarction, 1 patient died, and others recovered well and discharged. 7 patients with the operative therapy had no complication and mortality related to operation. The level of the D - dimmer in 20 cases decreased significantly after 2 weeks of the conservative or operative treatment （ t = 2. 629, P 〈 0. 05 ）. Conclusion Portal vein thrombosis should be diagnosed as soon as possible and treated with appropriate methods according to individualized condition of the patient.