非酒精性脂肪性肝病与代谢综合征相关性的临床研究

Non-alcoholic fatty liver disease and metabolic syndrome

目的分析非酒精性脂肪性肝病与代谢综合征的关系。方法按住院顺序选择有随访资料病例共185例,将其分为四组(单纯脂肪肝组、单纯肥胖组、脂肪肝+肥胖组、正常对照组),在基线水平对四组出现代谢综合征情况进行横向比较。其次,在随访后再次对四组出现代谢综合征情况进行组内、组间比较。结果随访结束时,单纯脂肪肝组代谢综合征发病率明显高于正常对照组(P<0.05)。结论非酒精性脂肪性肝病促进代谢综合征的发生,且不依赖于肥胖。

Objective To explore the possible relation between NAFLD and MS. Methods Collecting 185subjects with follow - up data, We divided all participants into four groups ： First, we contrasted the incidence rates of MS among all the groups. Then, after following up, we contrasted the incidence above - mentioned index among four groups. Results At the end of follow - up, the incidence rates of MS in fatty liver group were significantly higher than those in control group, independent of obesity. Conclusion NAFLD might promote the development of MS.