摘要
目的观察老年2型糖尿病患者心脏-脚踝血管指数(CAVI)与冠状动脉狭窄程度的相关性,评价CAVI对冠状动脉狭窄程度的预测价值。方法对60岁以上行冠状动脉造影异常患者,连续入选后进行CAVI测量、病史采集及血液化验检查,并分为A组(CAVI值≥9)及B组(CAVI值〈9),观察动脉硬化相关危险因素与CAVI的关系。入选患者分为糖尿病组及非糖尿病组,了解CAVI与血糖增高及冠状动脉病变程度的相关性。结果共入选298例冠心病患者,其中合并糖尿病者135例,无糖尿病者163例。CAVIi〉9.0者患糖尿病,多支病变者显著增多,并受年龄、体重指数、低密度脂蛋白等因素的影响。结论CAVI增高与冠状动脉硬化程度有一定的相关性。CAVI有助于预测冠状动脉硬化程度。
Objective To investigate the Relationship between CAVI (Cardio-Ankle vascular Index) and the degree of coronary artery stenosis in elderly patients with type 2 diabetes, the predictive value of CAVI were evaluated using the degree of coronary artery stenosis. Methods Relevant clinical data including CAMI, BMI, blood pressure, smoking, age, Sbp, Dbp, history and blood biochemistry test were collected in 60 years or older patients with coronary artery stenosis diagnosed by coronary angiography , and The 298 cases were divided into two groups, A group (CAVI≥ 9), B group (CAVI 〈 9), to investigate the correlativity among the level of CAVI and cardiovascular risk factors; at the same time All cases were assigned to group C (diabetes group) and group D( non-diabetic group), to Analyse the change of CAVI in coronary artery stenosis patients complicated with diabetes mellitus. Results A total of 298 eligible patients with coronary artery stenosis were enrolIed., including 163 non diabetics and 135 type 2 diabetics. The analysis result shows that there was a positive correlation among CAVI, Old age, BMI, LDL-C, multi-vessel lesion,diabetes. Conclusion The increase of CAVI was most highly related to the coronary artery stenosis. The level of CAVI might be a helpful predictive indexes to the severity of coronary atherosclerosis.
出处
《中华医学杂志》
CAS
CSCD
北大核心
2009年第32期2280-2282,共3页
National Medical Journal of China