4Amberger A,Maczek C,Jurgens G,et al.Co-expression of ICAM-1,VCAM-1,ELAM-1 and Hsp-60 in human arterial and venous endothelial cell in response to cytokines and oxidized low density lipoprotein[J].Cell Stress Chaperones,1997 ;2 (2):94-103.
5Takamatsu Y,Yuki S,Watanabe T.Studies on the concentration of 3-Methl-1-1-phenyl-2-Pyrazolin-5-one (MCI-186) in MCA occlusion and reperfusion model of rats[J].JPN Pharmacol Ther,1997; 25 (suppl):S1785-91.
6Tanaka M.Pharmacological and clinical profile of the free radical scavenger edaravone as a neuroprotective agent[J].Nippon Yakurigaku Zasshi,2002;119(5):301-8.
8Lee H, Zhu X, O'Neill MJ, et al. Altered expression of group Ⅰ and group Ⅱ metabotropic glutamate receptors in hippocampus of patients with Alzheimer's disease. J Neuropathol Exp Neurol, 2004, 63: 522-524.
9Bush AI, Martins RN, Rumble B, et al. The amyloid precursor protein of Alzheimer's dease. J Bio Chem, 1990,265:15977 -15983.
10Dawson A, Klingenburg M, Kramer R. Mitochondria:a practical approach. In: Darley VM, Rickword D. Wilson MT. eds. Transport across membranes. Oxfprd:IRL Press, 1987.35-77.
4American psychiatric association. Diagnostic and statistical manual of mental disorders(DSM-IV)[M]. 4th ed. Washington DC： Ameri- can Psychiatric Assodation, 1994 ： 143-146.
5Nasreddine Z S,Phillips N A, B4dirian V, et al. The Montreal Cognitive Assessment, MoCA： a briefscreening tool for mild cognitive impairment[J]. J Am Geriatr Soc, 2005,53(4) ：695- 699.
6Tohgi H,Abe T, Kimura M, et al. Cerebrospinal fluid acetyl- choline and choline in vascular dementia of Binswanger andmultiple small infarct types as compared with Alzheimer-type dementia[J]. J Neurol Trans, 1996,103(6) : 1211-1220.
7Corey Bloom J,Tiraboschi P,Hansen L A,et al. E4 allele dos- age does not predict cholinergic activity or synapse loss in Alzheimer s disease[J]. Neurology, 2000,54 (2) ： 403-406.
8Romdn G C. Brain hypoperfusion a critical factor in vascular dementia[J]. Neurol Res,2004,26(5):454-458.
9Frodl T, Meisenzahl E M, Mtiller D, et al. P300 subcompo- nents and clinical symptoms in schizophrenia[J]. Int J Psy- chophysiol, 2002,43(3) : 237-246.
