期刊文献+

粒细胞集落刺激因子及其受体在肺癌中表达与作用的研究进展 被引量:1

下载PDF
导出
摘要 粒细胞集落刺激因子(granulocyte colony-stimulating factor,G-CSF)被广泛应用于治疗肿瘤放、化疗所致的白细胞减少。研究发现,多种实体肿瘤中有G-CSF及粒细胞集落刺激因子受体(G-CSF receptor,G-CSFR)的表达,且G-CSF可通过G-CSF/G-CSFR的自分泌/旁分泌通路与环氧化酶通路等影响肿瘤细胞增殖、凋亡和微血管形成,但其确切机制尚需要进一步研究。本文就G-CSF及G-CSFR在肺癌中的表达及其作用机制的研究进展作综述。
作者 杨敏 胡春宏
出处 《肿瘤》 CAS CSCD 北大核心 2009年第8期812-815,共4页 Tumor
  • 相关文献

参考文献27

  • 1ARAKI K, KISHIHARA F, TAKAHASHI K,et al. Hepatocellular carcinoma producing a granulocyte eolony-stimulating factor : report of a resected case with a literature review [J]. Liver Int, 2007,27(5) :716-721.
  • 2INOUE C, KATO S, HIGUCHI K, et al. A case of malignant pleural mesothelioma with elevation of G-CSF and CYFRA in the serum and pleural fluid[ J]. Nihon Kokyuki Gakkai Zasshi,2007, 45 ( 3 ) :243-247.
  • 3TAKAHASHI H, YASUDA A, OCHI N, et al. Granulocyte-colony stimulating factor producing rectal cancer [ J ]. World J Surg Oncol 2008, 6:70.
  • 4ASONO S, URABE A, OKABE T, et al. Demonstration of granulopoietic factor(s) in the plasma of nude mice transplanted with a human lung cancer and in the tumor tissue[ J]. Blood, 1977,49 (5) :845-852.
  • 5KAIRA K, ISHIZUKA T, TANAKA H, et al. Lung cancer producing granulocyte colony-stimulating factor and rapid spreading to peritoneal cavity[ J]. J Thorac Onco1,2008,3 (9) :1054-1055.
  • 6KATSUMATA N, EGUCHI K, FUKUDA M, et al. Serum levels of eytokines in patients with untreated primary lung cancer[J]. Clin Cancer Res, 1996,2 ( 3 ) :553-559.
  • 7UEMURA Y,KOBAYASHI M, NAKATA H, et al.Effect of serum deprivatiom on constitutive production of granulocyte-colony stimulating factor and granulocyte macrophage-colony stimulating factor in lung cancer[ J]. lnt J Mol Mod,2004,109 (6) :826-832.
  • 8UEMURA Y, KOBAYAShHI M, NAKATA H, et al. Effects of granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor on lung cancer: roles of cyelooxygenase-2 [J]. Oncol Rep, 2007, 17(4) :955-961.
  • 9AZIZ M H, WHEELER D L, BHAMB B, et ctl. Protein kinase C delta overexpressing transgenic mice are resistant to chemically but not to UV radiation-induced development of squamous cell carcinomas: a possible link to specific cytokines and cyclooxygenase-2 [J]. Cancer Res, 2006 ,66(2) :713-722.
  • 10UEMURA Y, KOBAYASHHI M, NAKATA H, et al. Role of protein kinase C in expression of granulocyte-colony stimulating factor and granulocyte macrophage-colony stimulating factor in lung cancer[J]. Int J Mol Mod,2005,16( 5 ) :873-881.

同被引文献3

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部