急性期脑梗死与颈动脉粥样硬化斑块的关系

Correlation of acute ischemic cerebral infarction with carotid atherosclerosis plaque

目的:颈动脉粥样硬化是缺血性脑梗死最主要的病因和危险因素,通过彩色多普勒超声检测对急性期脑梗死患者与非脑血管病患者颈动脉粥样硬化斑块性质的对比研究,探讨颈动脉粥样硬化斑块与急性脑梗死的关系。方法:对MRI的弥散加权成像(DWI)证实的90例急性期脑梗死患者(脑梗死组)和82例非脑血管病患者(对照组),采用彩色多普勒超声方法分析患者颈动脉斑块的分布、形态、数量和回声特征。结果:脑梗死组斑块阳性率76.7%,明显高于对照组(32.9%,P<0.01);脑梗死组斑块以不均质斑块(61.1%)和不规则斑块(36.8%,P<0.01)为主,且梗死侧明显。结论:颈动脉粥样硬化斑块的性质和急性脑梗死的发生密切相关。

Objective ： Atherosclerosis of the carotid artery is the main cause and risk factor of ischemic cerebral infarction. We aim to evaluate the relation between acute ischemic cerebral infarction and the carotid atherosclerosis plaque. Methods ： The distribution, shape, number and echoic features of the carotid atherosclerosis plaques confirmed by MRI diffusion- weighted imaging （DWI） were analyzed by color Doppler uhrasonography in 90 patients with acute ischemic cerebral infarction （ Group A） and 82 controis （ Group B）. Results ： The positive rate of acute cerebral ischemic infarction was significantly higher in Group A （76.7%） than in Group B （32.9%, P 〈 0. 01 ）. And the plaque in Group A was main- ly characterized by irregularity （36.8 % ） and heterogeneity （ 61.1%, P 〈 0.01 ）. Conclusion. Ischemic cerebral infarction is strongly correlated with the nature of the carotid atherosclerosis plaque.