健脾补肾方联合艾灸对卵巢早衰患者生存质量及阴道脱落细胞成熟度的影响

Effect of Jianpi Bushen Formula Combined with Moxibustion on Quality of Life and Maturation Degree of Vaginal Exfoliate Cells in Premature Ovarian Failure Patients

目的评价健脾补肾方联合艾灸对卵巢早衰患者生存质量及阴道脱落细胞成熟度的作用。方法将55例卵巢早衰患者随机分为健脾补肾方联合艾灸治疗组33例和倍美力对照组22例,应用生存质量测定量表进行生存质量评定,依据阴道脱落细胞成熟指数(MI)、成熟价值(MV)对患者阴道脱落细胞成熟度进行评价。结果两组均能显著改善生存质量量表评分,并且除性生活维度外其他3个维度治疗组均优于对照组(P<0.05或P<0.01)。两组均能提高阴道脱落细胞成熟度,差异无统计学意义(P<0.05)。结论健脾补肾方联合艾灸可提高卵巢早衰患者生存质量和阴道脱落细胞成熟度。

Objective To evaluate the effect of Jianpi Bushen Formula（Formula for Invigorating Spleen and Nourishing Kidney） combined with moxibustion on quality of life（QOL） and maturation degree of vaginal exfoliate cells（MDVEC） in premature ovarian failure（POF） patients.Methods Totally 55 POF patients were randomized into treatment group（33 cases,treated by Jianpi Bushen Formula with moxibustion） and control group（22 cases,treated by Premarine）.Menopause-specified quality of life（MENQOL） was adopted to evaluate QOL of the patients. Maturation index （MI） and maturation value （MV） were applied to evaluate MDVEC. Re- suits The scores of MENQOL of both groups were improved and the effect of the treatment group （except sexual life dimension） was superior to that of the control group （P〈0.05 or P〈0.01）. In addition, MDVEC of both groups were significantly improved, without statistical difference（P〈0.05）. Conclusion Jianpi Bushen Formula can improve QOL and MDVEC of the patients with POF.