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非酒精性肝脂肪变性和脂肪性肝炎的发生机制 被引量:13

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摘要 非酒精性脂肪性肝病(Non—alcholic fatty liver disease,NAFLD)基本疾病谱有两种:非酒精性脂肪肝(non—alcohlic fattv liver,NAFL)和非酒精性脂肪性肝炎(Non—alcohlic steatohepatitism,NASH)。NASH为NAFLD中的一种组织学亚型,除了脂肪浸润外,可见到不同程度的肝细胞损伤、炎症和纤维化。“二次打击”假说认为,传统上认为如果肝脏能够适应脂肪变性的发生。则仅表现为单纯性脂肪肝:如果不能够适应,则发生脂肪性肝炎。
出处 《现代消化及介入诊疗》 2009年第4期237-242,共6页 Modern Interventional Diagnosis and Treatment in Gastroenterology
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