期刊文献+

脂肪肝与肝硬化肝癌 被引量:8

下载PDF
导出
摘要 脂肪性肝病(FLD)是指各种原因引起的肝细胞内过多的脂肪堆积,当脂肪含量超过肝重的5%即称为脂肪肝。FLD是一种遗传-环境-代谢应激相关性疾病.为发达国家和地区第一大慢性肝病,对人类健康和社会发展构成严重威胁。临床上FLD根据是否饮酒及饮酒量分为酒精性肝病(ALD)和非酒精性脂肪肝(NAFLD)。酒精性肝病是由于长期大量饮酒所致的肝脏疾病。病理学改变主要为大泡性或大泡性为主伴小泡性的混合性肝细胞脂肪变性。初期涌常表现为脂肪肝.讲而可发展成酒精件肝餐、酒精性肝纤维化和酒精性肝硬化,
出处 《现代消化及介入诊疗》 2009年第4期246-249,共4页 Modern Interventional Diagnosis and Treatment in Gastroenterology
  • 相关文献

参考文献9

  • 1Sussman S, Dent CW, Skara S, et al. Alcoholic liver disease (ALD): a new domain for prevention efforts. Subst Use Misuse, 2002,37: 1887-1904.
  • 2Cortez-Pinto H, de Moura MC, Day CP. Non-alcoholic steatohepatitis: from cell biology to clinical practice. J Hepatol, 2006,44:197- 208.
  • 3Adams LA, Angulo P. Recent concepts in non-alcoholic fatty liver disease. Diabet Med, 2005,22:1129-1133.
  • 4范建高,丁晓东,曾悦.非酒精性脂肪性肝炎:美国肝脏病学会专题研讨会纪要[J].肝脏,2003,8(2):59-61. 被引量:28
  • 5Caldwell S, Park SH. The epidemiology of hepatocellular cancer:from the perspectives of public health problem to tumor biology. J Gastroenterol, 2009,44(Suppl 19):96-101.
  • 6Marrero JA, Fontana RJ, Su GL, et al. NAFLD may be a common underlying liver disease in patients with hepatocellular carcinoma in the United States. Hepatology, 2002,36:1349-1354.
  • 7Hashimoto E, Yatsuji S, Tobari M, et al. Hepatocellular carcinoma in patients with nonalcoholic steatohepatitis. J Gastroenterol, 2009, 44(Suppl 19):89-95.
  • 8Calle EE, Rodriguez C, Walker-Thurmond K, et al. Overweight,obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N Engl J Med, 2003,348:1625-1638.
  • 9Nair S, Mason A, Eason J, et al. Is obesity an independent risk factor for hepatocellular carcinoma in cirrhosis? Hepatology, 2002,36: 150-155.

共引文献27

同被引文献136

引证文献8

二级引证文献23

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部