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COX-2及COX-2抑制剂与肿瘤防治 被引量:2

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摘要 环氧化酶-2(COX-2)是环氧化酶的诱导型,是合成前列腺素(PG)过程中一个重要的限速酶。COX-2在肿瘤细胞中存在着过度表达,提示它在肿瘤发生、发展、细胞凋亡和肿瘤血管生成方面发挥着重要作用,现已成为肿瘤防治的热门靶点;并也取得了可观的临床应用成果。本为拟就COX-2及其抑制剂与肿瘤的关系研究新进展作一综述。
作者 刘治坤 陈皇
出处 《牡丹江医学院学报》 2009年第4期80-83,共4页 Journal of Mudanjiang Medical University
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