婴儿巨细胞病毒感染临床及pp65抗原检测分析

Clinical analysis of cytomegalovirus infection and detection of its early antigen pp65 in infants

分析6例住院婴儿巨细胞病毒（CMV）活动性感染者的临床及诊断。结果示先天性感染和围产期感染各2例，其中CMV-IgM（＋）不能确定为活动性感染者，根据病情、体征，结合CMV-pp65（＋）可证实为CMV活动性感染。2例婴儿肺炎CMV—pp65（＋），诊断为CMV肺炎。提示pp65抗原较CMV-IgM更加证实CMV感染的活动性。

Clinical data of six infants with active cytomegalovirus （CMV） infection were analyzed, two congential infection, two pertnatal infection, one postnantal infection and one with both pnumonia and hepatitis caused by CMV. Serum CMV-IgM, CMV early antigen pp65 and CMV DNA were detected positive in the infants with damage in their tissues and organs within two weeks after their birth, thus diagmosis of active CMV infection was esrablished. MCV-pp65 antigrn is more uneful in diagnosis of CMV active infection than CMV-IgM.