超声引导下穿刺注射平阳霉素治疗肝血管瘤68例

Ultrasound-guided injection of pingyangmycin for treatment of liver hemangioma

目的：探讨超声引导下肝血管瘤内注射平阳霉素的疗效。方法：对68例肝血管瘤患者行超声引导下经皮穿刺注射平阳霉素（瘤体直径〈5 cm、5-8 cm、〉8 cm,用量分别为8 mg、16 mg和24-32 mg）。术后随访6个月。结果：治疗1次48例,治疗2次11例,9例治疗3次后均治愈,瘤体内血流消失,总有效率为100%。术后5例出现低热,8例出现上腹痛伴呼吸困难,2例出现恶心、呕吐,对症处理后症状消失。结论：超声引导下介入治疗肝血管瘤是一种操作简单、方便、易行,安全、无严重并发症,可用于临床治疗肝血管瘤的有效方法。

Objective：To assess the clinical effect of ultrasound-guided percutaneous injection of pingyangmycin on liver hemangioma. Methods ： Sixty-eight cases of liver hemangioma underwent ultrasound-guided percutaneous injection of pingyangmycin. For tumors with a diameter 〈5 cm,5 -8 cm and 〉8 cm,the dose was 8 mg,16 mg and 24 -32 mg,respectively. All the cases were followed up for 6 months. Results ： Forty-eight cases of liver hemangioma were cured by one operation, 11 cases were cured by 2 treatments and 9 cases by 3. The blood in the hemangioma vanished,with an overall effective rate of 100%. After the operation,5 patients had low fever,8 had upper abdominal pain and dyspnea, and 2 patients felt sick and vomited. After treatment, all the symptoms disappeared. Conclusions： Uhrasound-guided percutaneous injection of pingyangmycin is an effective therapy for treatment for liver hemangioma. It is safe, convenient, easy to operate and has few complications .