胆囊胆固醇结石的成因研究进展

Research Progress in Cholesterol Gallstone Pathogenesis

近几十年来胆囊结石的发病率呈逐渐上升的趋势。胆石成因尚未完全阐明。近年来,对胆汁成分的改变、细菌感染、致石基因、促成核因子和抗成核因子的失衡病理因素作了较多研究。从全世界范围来看,胆囊结石主要为胆固醇结石。该综述将从以上方面对胆固醇结石的发生机制进行阐述。

In recent decades the incidence of gallstone presents a gradual upward trend. The mechanism have not been fully clarified. In recent years, more research have been done on changes in composition of bile, bacterial infection, nuclear factors and the pathological imbalance of anti-nuclear factors. From all over the world,cholesterol gallstone is the main gallstone. This article reviews the pathogcnesis of of cholesterol gallstone.