益智汤治疗老年性痴呆38例

Treating 38 Cases of Senile Dementia in Yizhi Decoction

目的:观察益智汤治疗老年性痴呆(AD)的疗效。方法:将早中期AD患者73例随机分为治疗组和对照组,治疗组予益智汤,对照组用盐酸多奈哌齐治疗,治疗前后分别进行简易智能状态检查(MMSE)和日常生活自理量表(ADL)评定。结果:治疗组总有效率84.21%,对照组总有效率68.57%,两组有效率相比有显著性差异(P<0.05),治疗后两组MMSE、ADL比较均有显著性差异(P<0.05)。结论:益智汤汤治疗AD效果优于盐酸多奈哌齐。

Objective： To observe the clinical curative effect of Yizhi decoction to treat senile dementia. Methods ： 73 cases of senile dementia patient early metapbase were randomly divided into treatment and control. The treatment was treated in Yizhi decoction and the control was treated in hydrochloric acid donepezil. The evaluation of MMSE and the ADL was used before and after treatment. Results ： The total effective rate was 84.21% in the treatment and 68.57% in the control. The total effective rate,MMSE and ADL had the significant difference between treatment and control（ P 〈 0.05 ）. Conclusion： The Yizhi decoction had the better effect to treat senile dementia than hydrochloric acid donepezil.