摘要
对经X线骨密度仪检测L2~4的骨密度(BMD)诊断为绝经后骨质疏松(PMO)的86例妇女的血清雌二醇(E2)含量进行RIA测定.其E2含量均值为61.38pmol/L。对本组86例PMO妇女给予小剂量利维爱为主的联合用药治疗6个月.对照观察用药前后BMD、血清钙(Ca)、磷(P)、碱性磷酸酶(ALP)的变化。结果显示.用药后BMD均有不同程度的提高.以绝经时间≤10年者尤为明显(P<0.01);绝经时间>10年者虽有提高.但差异不显著(P>0.05)。治疗前血清Ca增高30例.占34.88%;P降低29例.占33.72%;ALP增高51例.占59.3%。治疗后均恢复正常。提示联合用药可减少利维爱的用量,是PMO较为理想的治疗方案。绝经后任何时期用药都可防止骨的继续丢失,早期治疗效果更好。
Test a kind treatment for postmenopausal osteoporosis(PMO) of women. We have treated the 86 case of women with PMO with comprehensive treatment mainly with low-dosage of LwiAL for six months,and observed. their BMD increased obviously,specially whose meropausal time were less than 10 years (P< 0. 01),Ca,P.ALP in sera returned to normal. The above treatment is more effective comparely and may reduce the dosage of LIVIAL.
出处
《中国老年学杂志》
CAS
CSCD
北大核心
1998年第4期223-225,共3页
Chinese Journal of Gerontology