得舒特联合黛力新治疗肠易激综合征120例分析

The analysis of Pinaverium Bromide combined with Deanxit in the treatment of 120 cases of irritable bowel syndrome

目的:观察得舒特联合黛力新对肠易激综合征(IBS)患者的治疗效果。方法:将238例肠易激综合征门诊患者随机分成对照组(118例)和观察组(120例)。对照组给予得舒特50mg,3次/d。观察组给予得舒特50mg,3次/d;黛力新1片,2次/d。比较两组患者的综合疗效及不良反应。结果:观察组总有效率(显效+有效)为97.50%,对照组总有效率为73.73%,两组总有效率经统计学处理,有显著性差异(P<0.05)。两组药物耐受性及安全性良好,整个疗程未见明显毒副作用,实验室检查如肝、肾功能等未见异常。结论:得舒特联合黛力新治疗肠易激综合征有较好的疗效,毒副作用小,值得临床应用。

Objective： To observe the therapeutic effect of Pinaverium Bromide combined with Deanxit in the treatment of irritable bowel syndrome （IBS）. Methods： 238 cases of patients with IBS were randomly divided into control group （118 cases） and observation group （120 cases）. The control group was given 50 mg Pinaverium Bromide, three times a day; the observation group was given one pill of Deanxit, two times a day, and 50 mg Pinaverium Bromide, three times a day. Then the therapeutic effect and side effect of two groups were compared. Results： The total effectiveness （marked effectiveness and effectiveness） of observation group and control group were 97.50% and 73.73% respectively, they showed significant difference （P〈0.05）. Patients medicine tolerance and security of two groups were good, no obvious poisonous side effect was observed in the whole course, the laboratory inspection such as hepatic and renal function and so on showed no abnor- mality. Conclusion： The effect of Pinavcrium Bromide combined with Deanxit in the treatment of IBS is good, its poisonous side effect is small and worth using in clinic.