1538例孕妇及其胎儿人微小病毒B19检测

Human Parvovirus B19 Infection in Pregnant Women and their Neoantes in Guangzhou

目的：了解广州地区孕妇和胎儿人微小病毒B19感染状况及传播途径。方法：对1538例孕产妇进行母血及脐血微小病毒DNA检测。结果：发现微小病毒B19孕产妇检出率1。04％，脐血检出率0．26％，并在胎盘组织发现2例微小病毒B19阳性。结论：广州地区孕产妇存在微小病毒B19的感染，并通过胎盘传播给胎儿。

Objective:To stued the perinatal infection of human parvovirus B19 in pregnant women and their fetuses inGuangzhou. Methods:1538 sera ofnormal pregnant women in two hospitals were investigated by polymerase chain reaction (PCR)to check the parvovirus B19 DNA. Results:The prevalence of parvovirus B19 DNA was 1.04% and 0.26% in the sera of normalpregnant women and umbilical cords respectivly. PVB19 DNA was found in the placenta of two pregnant women . Conclusion:Theresults suggest that parvovirus B19 infection do exist in pregnant women and their neonates as well as fetuses in Guangzhou.PVB19 transmitted via the placenta were the main sources for the neonatal infection.