婴儿指部纤维瘤病

Infantile digital fibromatosis:a case report

报告1例婴儿指部纤维瘤病。患儿男,21个月。左手无名指和小指末节出现结节,皮肤萎缩20个月余。系统检查无异常。皮损组织病理检查:表皮角化过度伴角化不全,棘层肥厚,表皮突延长、增宽。真皮成纤维细胞及胶原增生,胞质内可见嗜伊红包涵体。Masson染色胞质中可见圆形深紫色的包涵体。结合临床诊断为婴儿指部纤维瘤病。

A case of infantile digital fibromatosis is reported. A 21-month-old boy presented with asymptomatic, gradually enlarged nodules on the atrophic skin of terminal phalanges of the fourth and fifth fingers of his left hand for 21 months. Histopathology showed hyperkeratosis, parakeratosis, acanthosis and elongation and widening of rete ridges of the epidermis, proliferation of fibroblasts and collagen of the dermis. Eosinophilic inclusion bodies were seen in the cytoplasm of the fibroblasts, which were round and dark purple with Masson staining. This case was diagnosed as infantile digital fibromatosis.