部分脾栓塞在继发性脾功能亢进中的应用现状

Clinical application of partial splenic embolization in treating secondary hypersplenism

脾功能亢进(脾亢)发生于各种原因的脾淤血,是一种常见病,随着介入放射学的发展,部分脾栓塞术(PSE)在临床上已经广泛应用,其在继发性脾亢中的应用越来越多。有多种栓塞材料可用于PSE,且各有优缺点。由于脾脏血管的解剖特点,栓塞体积大小直接影响PSE治疗效果。评价PSE的疗效,可以根据外周血象、免疫功能、血流动力学指标和肝功能进行观察。由于种种原因,PSE在临床应用过程中存在一些不足,亟待加以完善。

The hypersplenism is a common disease caused by cirrhosis of different reasons. With the development of interventional radiology, partial splenic embolization （PSE） has been widely applied in clinical practice, especially in the treatment of secondary hypersplenism. There is a variety of embolization materials used in PSE, each has its own merits. Because of the anatomical characteristics of the splenic artery, the embolized volume and extent of the spleen will direetly affeet the therapeutic results. Peripheral blood test, immunological function, hemodynamics and hepatic function can be used to evaluate the effects of PSE. Owing to a variety of reasons, there are still some shortages of PSE in clinical practice, which are badly in need of being improved.