慢性心力衰竭患者发生心肾综合征的临床特点分析

The Clinical Features of the Occurrence of Cardiorenal Syndrome in Patients with Chronic Heart Failure

目的探讨慢性心力衰竭患者发生心肾综合征的临床特点。方法采用回顾性分析方法对356例慢性心力衰竭患者心肾综合征的特点进行分析。结果心肾综合征发生率24．2％（86／356）；冠心病（缺血性心肌病）、肺源性心脏病、高血压性心脏病是其发生的三大主要原因；肾功能损伤以中度为主，GFR30～59ml／min占72．1％（62／86），15—29ml／min占12．81％（11／86），〈15ml／min占15．1％（13／86）；用血管紧张素转化酶抑制剂（ACEI）、利尿剂、β受体阻滞剂、血液净化、促红素和铁剂有一定疗效。结论部分慢性心力衰竭患者可发生心肾综合征，肾功能以中度损害为主，临床治疗有一定疗效。

Objective To discuss the clinical features of the occurrence of eardiorenal syndrome in patients with chronic heart failure. Methods A retrospective analysis was made to the features of the occurrence of cardiorenal syndrome in 356 cases with chronic heart failure. Result The occurrence rate of cardiorenal syndrome was 24. 2% （ 86/356 ） ; coronary heart diseases （ ischemic eardiomyopathy） ,pulmonary heart disease and hypertensive heart disease were the 3 main causes; the renal function impairments were mainly at moderate level： 72. 1% （ 62/86 ） showed GFR30 - 59ml/min, 12.81% （11/86 ） showed GFR15 - 29ml/min and 15. 1%（13/86 ） showed GFR 〈 15ml/min; the application of angiotensin converting enzyme inhibitor （ACEI）, diuretics,13 - receptor blockers, blood purification, erythropoietin （ EPO ） and ferralia was of certain effect. Conclusions Some patients with chronic heart failure may have the occurrence of eardiorenal syndrome with moderate renal function impairments ,the present clinical therapy is of certain effect.