疏肝和胃化瘀法改善功能性消化不良胃动力的临床研究

Clinical Study of Functional Dyspepsia Treated by a Method of Shuganheweihuayu

目的:观察疏肝和胃化瘀法治疗功能性消化不良(functional dyspepsia FD)的临床疗效。方法:将153例FD患者随机分为两组。治疗组78例,以疏肝和胃化瘀法治疗;对照组75例,以疏肝和胃法治疗,两组均4周为1个疗程。观察两组临床疗效和治疗前后症状积分改变及胃排空障碍的改善情况。结果(:1)治疗组临床总有效率(88.46%)明显优于对照组(72%,P<0.05);(2)治疗组治疗后,症状积分由(31.14±11.81)降低到(8.58±6.39),治疗组对改善FD症状有非常显著效果(P<0.01)(;3)治疗组治疗后,症状积分(8.58±6.39)明显低于对照组(13.77±9.21,P<0.01);(4)治疗治疗后,空腹氢呼气浓度由(31.26±7.07)ppm降低到(10.83±7.89)ppm,治疗组经治疗后空腹氢呼气浓度较治疗前有非常显著下降(P<0.01);(5)治疗组治疗后空腹氢呼气浓度(10.83±7.89ppm)低于对照组(15.81±11.24ppm,P<0.05);(6)治疗组的胃排空障碍好转率(89.36%)优于对照组(69.77%,P<0.05)。结论:疏肝和胃化瘀法治疗FD的疗效优于疏肝和胃法,疏肝和胃化瘀法能促进胃排空,明显改善FD患者的临床症状,提高临床疗效。

Objective ： To observe the clinical effect of a methods of Shuganheweihuayu on the treatment of functional dyspepsia（FD）.Methods：153cases of functional dyspepsia were randomly divided into two groups.78cases in treatment group were treated by a method of Shuganheweihuayu, and 75cases in control group were treated by a method of Shuganhewei.With a treatment course of four weeks in both groups, the therapeutic effect was analyzed by observation of symptom score, improvement and gastric emptying dysfunction. Results ： （ 1 ） The total effective rate in treatment group （ 88.46% ） was markedly higher than that in control group（72%, P〈0.05）. （ 2 ） The symptom score was obviously lower in treatment group （ 8.58 ± 6.39 ）after treatment （ 31.14± 11.81 ,P〈0.01 ）. （ 3 ）The symptom score was markedly lower in treatment group （ 8.58 ±6.39 ） compared to which of control group （ 13.77± 9.21, P〈0.01 ）. （ 4 ） FBH concentration in treatment group（10.83 ±7.89ppm） had obviously descended after treatment （ 31.26 ±7.07ppm, P〈0.01 ）.（ 5 ） FBH concentration in treatment group（10.83±7.89ppm） had descended compared to which of control group （ 15.81 ±11.24ppm, P〈0.05 ）. （ 6 ）Comparing with the control group （ 69.77% ）, The treatment group improved the gastric emptying dysfunction effectively （ 89.36%, P〈0.05 ）.Conclusion： The clinical effect of a methods of Shuganheweihuayu on the treatment of functional dyspepsia is superior to a methods of Shuganhewei. A methods of Shuganheweihuayu could raise effect of functional dyspepsia, obviously improve symptoms and gastric emptying dysfunction.