抗敏颗粒质量标准研究

Study on Quality Standards of Kangmin Granule

目的：建立抗敏颗粒剂的质量标准。方法：采用薄层色谱法对抗敏颗粒剂中的当归、桂枝进行薄层色谱鉴别；采用高效液相色谱法对黄芩中的黄芩苷的含量进行测定。结果显示：试验采用薄层色谱法定性鉴别，色谱斑点清晰，分离度良好，阴性液无干扰；以HPLC法测定本品黄芩中的黄芩苷的含量，方法精密度、稳定性、重复性良好，回收率在98．1%-100．6％之间，RSD为1．5％。结论：本试验所确定的质量分析方法稳定可靠，能较为合理地对处方中各组分进行定性、定量检测，重复性强，可作为的抗敏颗粒剂的质量标准。

Objective： To establish the quality control method for Kangmin granule. Methods：Radix angelieae sinensis and Ramulus cinnamomi was identified by TLC; and the content of Baicalin were determined by HPLC.Result： the spots on the TLC are clear, The determination of Baicalin showed a good linear relationship at arrange of from 0.0944 to 0.9440 μg, the average recoveries of Baiealin was from 98.1% to 100.6%, RSD was 1.50%.Conclusion ： the qualitative and quantitative analytic methods are stable, reliable and easy to repeat. It can be applied as the standard of Kangrnin Granule.