生肤灵促进人体皮肤缺损修复的临床研究

Clinical Study of Shengfuling on Skin Defect Healing of Human Body

目的研究生肤灵在各种人体皮肤缺损创面修复中的疗效。方法将不同皮肤缺损的60例患者按随机单盲原则分为生肤灵组(治疗组)和常规外科换药组(对照组),分别给予治疗,观察2组不同创面愈合所需的时间、不同皮肤缺损程度下创面修复所需时间和愈合后的皮肤颜色、硬度和张力,并进行比较。结果生肤灵治疗组在创面愈合速度和愈合后的皮肤质地方面优于常规外科换药对照组(P<0.05)。治疗组在创面表面积缩小及皮肤再生方面均有显著疗效(P<0.05)。结论生肤灵可以诱导皮肤恢复正常的结构,促进缺损皮肤再生,具有明显的促进各种类型皮肤创面愈合的作用。

Objective To study the therapeutic effect of Shengfuling on the healing of various skin defect of human body. Methods Sixty cases of various skin defects were randomly divided into the treated group and the control group, which were treated by Shengfuling and normal healing after debridement, respectively. The healing time of defect areas and skin injury degrees was observed. The post-healing skin quality （color, hardness, tension） of the two groups were compared. Results The treated group had better effect than the control group in skin healing velocity and post-healing skin quality （P 〈0.05）. The treated group had remarkable effects on the wound reduction and skin regeneration （P 〈0.05）. Conclusion Shengfuling can induce skin recovering with normal composition, and accelerate the skin regeneration. It has a significant function of promoting the healing of various skin defects.