风湿性心脏病二尖瓣狭窄经皮球囊扩张术对肺功能的影响

Effect of percutaneous balloon mitral valvotomy on pulmonary function in patients with mitral stenosis

目的：了解风湿性心脏病（ＲＨＤ）二尖瓣狭窄（ＭＳ）经皮球囊二尖瓣扩张术（ＰＢＭＶ）对肺功能的影响。方法：对２２例ＲＨＤＭＳ患者ＰＢＭＶ术前和术后长达１年的肺功能随访。结果：所有病员术后均康复出院，无明显并发症，无死亡。ＰＢＭＶ术后２周，患者的通气功能与术前相仿；术后３周起到１年患者的通气功能指标有所改善，但肺的一氧化碳弥散功能（ＤＬＣＯ）反而减退。结论：ＲＨＤＭＳＰＢＭＶ术后３周起患者的通气功能指标有所改善，但肺的ＤＬＣＯ反而减退，减退的原因。

Objective:To study the effect of percutaneous balloon mitral valvotomy (PBMV) on pulmonary function in patients with rheumatic mitral stenosisMethods:Pulmonary function was assessed in 22 patients with mitral stenosis before and at varying intervals (2 weeks to 24 months)after PBMVResults:All patients were completely recoveredThe pulmonary function was not significantly different from that before operation and 2 weeks after PBMVThere were slight increase in pulmonary functions (FVC,FEV1,V50 and V25)at 3 weeks to 24 months after PBMVBut a significant decrease in diffusing capacity was observed Conclusion:The pulmonary function was slightly increased 3 months after PBMV,but the diffusing capacity was significantl decreasedThe hypothesis is that successful PBMV increases pulmonary function but does not improve the diffusing capacity at 3 weeks to 24 month period,these may be due to 95 decrease of capillary volume and irreversible structural damage of the lungs.