30例回盲部原发性恶性淋巴瘤临床分析

Primary ileocecal lymphoma: report of 30 cases

目的探讨回盲部原发性非霍奇金恶性淋巴瘤（ＮＨＬ）的最佳治疗方案。方法对１９６８年６月至１９９３年９月收治的３０例回盲部原发ＮＨＬ的临床资料进行了回顾性分析。结果３０例患者均行手术探查，手术切除率为９３％，２２例切除术后行ＣＯＰ或ＣＨＯＰ方案化疗，１１例再辅以局部放疗。３０例患者均为术后病理确诊，病理类型均属ＮＨＬ，其中Ｂ细胞源性２９例，Ｔ细胞型１例。按ＡｎｎＡｒｂｏｒ国际分期，Ⅰ期１１例、Ⅱ期１１例、Ⅲ期４例、Ⅳ期４例。患者５年生存率为３６６７％。结论病期早晚、治疗方法的选择是影响预后的主要因素。

Objecitve To investigate the best therapeutic method for primary ileocecal nonHodgkin′s lymphoma. Method Clinicopathologic features of 30 patients who had been treated from June 1964 to September 1993 were analyzed retrospectively. Result Twentyeight patients (93%) underwent resection of their disease.Eleven patients had the resection followed by chemotherapy.Eleven patients had the resection followed by chemotherapy and radiotherapy.All had pathologic evidence.Twentynine patients were categorized as Bcell type NHL.One had Tcell lesion.Eleven patients had stage I disease,11 stage II,4 stage III,and 4 stage IV.The 5year survival rate was 36.67%. Conclusion The prognostic factors are stage of the disease and treatment modality.Adequate initial surgery combined with radiotherapy and chemotherapy may provide optimum therapy for patients with primary ileocecal lymphoma.