摘要
研究麻醉时用小剂量(1.0mg)氟哌啶对腹腔镜胆囊摘除术(LC)术后恶心呕吐的预防效果及其不良反应。方法:观察78例LC病人,用药组38例,对照组40例,对比术中平均动脉压(MAP)、HR、麻醉恢复室(PACU)评分、术后恶心呕吐发生率等。结果:用药组恶心呕吐发生率(13.2%)明显低于对照组(32.5%)(P<0.05),MAP、HR、PACU评分在组间无显著差异。结论:小剂量氟哌啶能有效预防LC术后恶心呕吐,对麻醉无明显影响。
Objective: To evaluate the efficacy and adverse effects of low-dose droperidol(1. 0 mg) in preventing postoperative nausea and vomiting (PONV) of laparoscopic cholecystectomy (LC). Methods: Seventy-eightLC patients under standardized anesthesia were randomly divided into a prophylactic group (n= 38) and a controlgroup (n= 40). Parameters studied included MAP,HR changes in surgery, post-anesthesia care unit (PACU),score and PONV episodes after surgery recorded by ' blinded' nurses. Results: The incidence of PONV in theprophylactic group (13. 5 % ) was significantly lower than that of the control group (32. 5 % ), (P<0. 05). MAP,HR in surgery, PACU score and PACU observation time showed no significant difference between the twogroups (P>0.05 ). Conclusion: Low-dose droperidol (1. 0 mg ) administered in anesthesia reduces the incidenceof PONV of LC with neither circulation interference in surgery nor recovery delay of anesthesia.
关键词
腹腔镜
胆囊切除术
恶心
预防
控制
氟哌啶
Cholecystectomy laparoscopy/adv eff
Droperidol/admin
Nausea/prev
Vomiting/prev