皮肌炎患者运动单元电位的定量分析

Quantitative Analysis of Motor Unit Potential in Patients with Dermatomyositic Disease

为了更好地诊断皮肌炎，作者检测了３７例皮肌炎患者的骨骼肌肌电图，观察其电生理变化。结果显示疾病组患者患肌运动单元电位（ＭＵＰ）平均时程、波幅、上升时限、面积、面积波幅比及波形指数均较正常对照组降低（Ｐ＜０．０５或Ｐ＜０．０１），其中尤以波形指数和面积的改变显著（Ｐ＜０．０１），但患者左右两侧肌肉ＭＵＰ比较没有显著性差异（Ｐ＞０．０５）。认为ＭＵＰ定量分析对皮肌炎的诊断具有重要意义，ＭＵＰ波形指数和面积具有临床应用价值。

To diagnose dermatomyositic disease well, we adopted the method of EMG in an investigation of 37 patients. Their electrophysiologic parameters of 220 muscles were determined. The results showed that the parameters, including the average DUR, AMP, RISE, AREA, AR/AM and SI of motor unit potentials (MUPs) were significantly lower than those of the controls (P<0.05 or P<0.01), especially AREA and SI (P<0.01). But no remarkable difference was found between the muscles on the two sides of the diseased extremties. These findings suggest that quantitative analysis of MUPs is of importance to diagnosis of dermatomyositic disease and the parameters such as AREA and SI may provide more valuable information.