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急性心肌梗塞患者肺炎衣原体感染的血清学研究 被引量:4

Assessment of serology for detection of Chlamydia pneumoniae in patients with acute myocardial infarction
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摘要 目的了解急性心肌梗塞病人肺炎衣原体感染程度。方法采用间接显微免疫荧光法检测36例急性心肌梗塞病人和73例健康献血员血清肺炎衣原体IgG和IgM滴度。结果急性心肌梗塞组肺炎衣原体既往感染率(83.3%)明显高于对照组(31.5%),两组急性感染率差别无显著性。结论肺炎衣原体既往感染在冠状动脉粥样硬化性心脏病和急性心肌梗塞发病中具有一定的影响。 Objective To evaluate serology for detection of Chlamydia pneumoniae (C. Pneumoniae) in patients with acute myocardial infarction and normal subjects. Methods Microimmunoflorescence(micro-IF) test for IgG and IgM antibodies to C. pneumoniae specific antigen was performed in every subject. Results Thirty patients(83.3%) with micro-IF IgG titres were equal to or greater than 1∶16 and equal to or lower than 1∶256 while only 31.5% in control normal subjects and no difference in IgM antibody titer. Conclusion There was a significant association between past infection of C. Pneumoniae and acute myocardial infarction.
机构地区 安徽省立医院
出处 《安徽医科大学学报》 CAS 1998年第4期278-279,共2页 Acta Universitatis Medicinalis Anhui
关键词 感染 心肌梗塞 肺炎衣原体 血清学 hlamydia pneumoniae chlamydia infections myocardial infarction fluoroimmunoassay
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参考文献7

  • 1Saikku P, Leinonen M,Tenkanen L et al.Chronic Chlamydia penumonine infection as a risk factor for coronary heart disease in the Hesinki Heart study.Ann Intern Med,1992;116(3):273-278.
  • 2倪安平,王辉,董平,李永哲,王仲,朱元珏.肺炎、支气管炎和急性上呼吸道感染患者肺炎衣原体感染的研究[J].中华内科杂志,1995,34(6):388-391. 被引量:45
  • 3Ross R. The pathogenesis of atherosclerosisan update.N Engl J Med, 1986;314(8):458-500.
  • 4Steinberg D, Parthasarathy S, Carew TE et al. Beyond cholesterol. Modifications of Lowdensity Lipoprotein that increase its atherogenic ity.N Eegl J Med,1989;320(14):915-924.
  • 5Melnick SL, Shahar eL, Folsom AR et al.Past Infection by Chlamydia pneumoniae strain TWAR and asymptomatic Carotid atherosclerosis. Am J Med.1993;95(5):499-504.
  • 6Saikku P, Leinonen M, Mattila K,et al.Seroogical evidence of an association of a novel Chlamydia.TWAR, With Chronic coroarry heart disease and acute myocardial infarction,Lancet 1988;2(20):983-986.
  • 7Thom DH,Wang SP ,Grayston JT et al. The association between chlamydia pneumoniae strain TWAR antibody and angiographi cally demonstrated coronary artery disease.Arterioscler Thromb,1991;11(5):547-551.

二级参考文献2

  • 1倪安平,中华医学杂志,1994年,74卷,416页
  • 2Wang S P,J Clin Microbiol,1979年,10卷,259页

共引文献44

同被引文献29

  • 1董吁钢,孙晓欣,宁波.急性冠脉综合征患者血清肺炎衣原体、人巨细胞病毒感染的血清学研究[J].岭南心血管病杂志,2000,6(4):237-239. 被引量:7
  • 2冯根宝,鲁刚,朱清於,詹化文,胡兰萍,施毅.动脉粥样硬化症与肺炎衣原体感染——91例尸检结果报告[J].医学研究生学报,1999,12(2):36-39. 被引量:13
  • 3倪安平,王辉,董平,李永哲,王仲,朱元珏.肺炎、支气管炎和急性上呼吸道感染患者肺炎衣原体感染的研究[J].中华内科杂志,1995,34(6):388-391. 被引量:45
  • 4Saiku P, Leinonen M, Mattilak, et al. serological evidence of anassociation of novel chlamydia TWAR, with chronic coronary heart disease and acute myoemial infarction. Lancet, 1988,2:983 ~ 985.
  • 5Thom DH, Wang SP, Grayston JT, et al. Chlamydia pneumoniae strain TWAR antibody and angiographically demonstrated coronary. artery disease. Arterioscler Thronb, 1991,11: 547 ~ 551.
  • 6Blasi- F,Cosentini- R,Rauanell- R,et al.A possible association of chlamydia pneunoniae infection and acute myocardial infartion in patients younger than 65 yearn of age. Chest, 1997,112 (2):309 ~ 312.
  • 7Jens Boman. High prevalance of chlamyda neumoniae DNA in peripheral blood mononuclear cells in pail ents with cardiovascular disease and in middle - aged blood donors. The Journal of Infectious Disease, 1998,178: 247 ~ 7.
  • 8Berk BG, Weintrand WS, Alexander PW, et at. Measmenment of serum C- reactive proein concentration in myocardial ischemia and infarction. Br Heart J, 1992,47:249 ~ 43.
  • 9An derson- JL. Evaluation of C- reactive protein,an inflammatory marker, and infections serology as risk factors for coronary artery disease and myocardial infarction. J- Am- Cou-carliol, 1998,31(2) :35 ~ 41.
  • 10DahlenGH,StenlundH.Lp(a)lipoproteinisamajorriskfactorforcardiovasculardisease:pathogenicmechanismsandclinicalsignificance[J].ClinGenet.,1997;52:272-280.

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